Study finds, No Additional Benefits of Tissue Adhesives for
This systematic review aimed to compare the performance of tissue adhesives (TA) as an adjunct or closure method with traditional wound-closure methods (WCM) for cutaneous closure in arthroplasty and evaluate whether they have any added benefits in terms of decreasing wound complications and increasing post-operative patient satisfaction.

Randomized controlled trials (RCT) was done comparing outcomes of TA with emphasis on skin closure time, in-hospital stay, complication rates, cosmetic scoring systems (CSS), and patient satisfaction scores (PSS) compared to subcutaneous sutures (SCS) and skin staples (ST) in arthroplasty. The quality of RCTs was assessed using the NIH quality assessment tool.

--Ten RCTs were included. The pooled and the subgroup analysis revealed no significant difference in the wound infection rates, discharge rates, dehiscence rates, and PSS between TA and SCS or ST.

--TA was significantly associated with a longer time to closure compared to ST and a shorter time compared to SCS as a closure method. Length of stay was comparable in all groups.

To summarize, using TA in conjunction with subcuticular sutures or skin staples, or as a cutaneous technique of closure, did not provide extra benefits in terms of shortened hospital stays, lower infection rates, or faster wound healing. The scars PSS and pain scores appear to be comparable to those of typical WMCs.