Study finds, Utility & Efficacy of IOLMaster 700 SS-OCT in D
A Study was conducted to assess the efficacy of IOLMaster 700 (IOLM) biometer swept-source optical coherence tomography in detecting macular pathology before cataract surgery and to compare IOLM SS-OCT characteristics of foveal pathology with a widely used spectral-domain OCT (SD-OCT) system.

Retrospective analysis of 1156 consecutive eyes with IOLMaster 700 SS-OCT undergoing cataract surgery was performed. Approximately a third of these eyes (327 eyes) also had a SD-OCT scan performed previously. A single reviewer assessed each SS-OCT scan and identified them as “normal” or “abnormal.” SS-OCT sensitivity and specificity in identifying foveal pathology was assessed using findings on Spectralis SD-OCT scans as the gold standard.

--Of 327 eyes with both IOLM SS-OCT and Spectralis SD-OCT scans, 121 eyes had abnormal SS-OCT scans. Of these 121 eyes, SD-OCT scans confirmed pathology in 104 eyes.

--Of the remaining 206 eyes graded to have normal SS-OCT scans, 84 eyes had normal SD-OCT scans, and 122 eyes had pathologic findings on SD-OCT scans.

--For each pathologic condition, subtle but definitive differences existed in the appearance of the IOLM SS-OCT and SD-OCT images.

Finally, using a normal or abnormal Spectralis SD-OCT scan as confirmation of the absence or presence of foveal pathology, a high positive predictive value (86.0 %) of an abnormal IOLM SS-OCT scan and a high specificity (83.2 %) but low sensitivity (46.0%) and negative predictive value (40.8 %) of a normal-appearing SS-OCT scan was discovered. These findings imply that an abnormal IOLM SS-OCT scan in a healthy eye is a significant predictor of an aberrant macula and should prompt further assessment of the retina to rule out pathology prior to cataract surgery.