Study finds, Vitrectomy for diabetic macular edema and the r
A Study was conducted to evaluate the relevance of external limiting membrane (ELM) on the visual and morphological results in eyes with diabetic macular edema (DME) that underwent pars plana vitrectomy (PPV) with epiretinal membrane (ERM) and internal limiting membrane (ILM) peeling.

Researchers assessed preoperative and postoperative best-corrected visual acuity (BCVA), central macular thickness (CMT) using spectral domain OCT (optical coherence tomography). The surgeries were performed using 23- or 27-gauge vitrectomy. The ELM was graded depending on its configuration.

--99 eyes were enrolled. The postoperative follow up averaged 23.7?months.

--The preoperative and final BCVA averaged 0.71?±?0.28 and 0.52?±?0.3 logMAR, respectively.

--The CMT averaged 515.2?±?209.1?microm preoperatively and 327?±?66.1?microm postoperatively.

--Eyes with intact ELM (n?=?8) had a significantly better BCVA compared to those with ELM disruption. The final CMT was similar among the groups.

Finally, PPV combined with ERM and ILM peeling is a successful DME treatment. Preoperatively intact ELM eyes had a considerably better visual result. As long as the ELM is intact, we propose early PPV for patients with DME to optimize the benefit.