The efficacy of diffusion-weighted MRI in the diagnosis of o
The apparent diffusion coefficient (ADC) is effective for the quantitative evaluation of mandibular osteomyelitis. The study was published in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology.

This retrospective cohort study aimed to determine the diagnostic utility of apparent diffusion coefficient (ADC) values in the quantitative evaluation of mandibular osteomyelitis.

Researchers analyzed the records of 70 patients aged 30?90 years, with and without osteomyelitis, who underwent magnetic resonance imaging. The mean ADC of the bone marrow of patients without osteomyelitis and those with acute and chronic osteomyelitis of the mandible were calculated. Differences in ADC overall and in pair-wise comparisons were analyzed. Correlations with patient age were also calculated.

- The mean ADC values in the non-osteomyelitis, acute osteomyelitis, and chronic osteomyelitis groups were 0.87 ± 0.15?×?10?3 mm2/s, 1.24 ± 0.11?×?10?3 mm2/s, and 1.07 ± 0.13?×?10?3 mm2/s, respectively.

- Receiver operating characteristic curve analysis revealed an ADC cutoff of 0.98 for osteomyelitis.

- Diagnostic values for predicting osteomyelitis were ? .81. No correlations of osteomyelitis with age were found.

In summary, the ADC was significantly higher in the osteomyelitis group than in the non-osteomyelitis group. This suggests that ADC may be a useful parameter for the quantitative evaluation of mandibular osteomyelitis.